chemagic™ Prime™ Instrument
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- Fully automated DNA/RNA extraction, normalisation, and PCR setup in one walk-away system.
- High-throughput capacity: Processes 1–192 samples per run; handles sample volumes from 50 µL to 10 mL.
- Patented M-PVA Magnetic Bead Technology for high yields and purity, proven for NGS, PCR, MLPA, and long-read sequencing.
- Flexible sample compatibility: Blood, saliva, plasma, swabs, wastewater, and more.
- Integrated barcode scanning and LIMS-compatible tracking for traceability and compliance.
- User-friendly touchscreen interface with intuitive software and fast setup.
- On-deck heating, cooling, shaking, and UV disinfection for workflow optimisation and safety.
- Compact design for high-throughput labs requiring reliable, automated nucleic acid purification.
For research use only. Not for use in diagnostic procedures.
Optional accessories are available for purchase separately. If you require a customised solution, please contact our technical specialists by selecting the "Add to enquiry" button and using our enquiry form or at sales@lasec.com.
Installation, training and special delivery requirements, such as the need for tail-lift trucks and additional labour and installation for large equipment and hazardous material (Hazmat) packaging, are chargeable in addition to standard freight and will be quoted separately before dispatch.
Online ordering is currently limited to South African customers, but our full range is still available. If you are ordering from outside South Africa, please log an enquiry or email internationallabsales@lasec.com, and our international sales team will gladly assist you through our traditional sales channels.
Availability:On Request
SKU
IREVCHEMPRIME
BrandRevvity
Fully Automated DNA and RNA Isolation, Normalisation, and PCR Setup for Research Workflows
Overview
The chemagic™ Prime™ Instrument is a next-generation, fully automated system for DNA and RNA purification, designed to streamline complex laboratory workflows by integrating:
- Primary sample transfer
- DNA/RNA extraction using M-PVA Magnetic Bead Technology
- Optional normalization
- PCR setup
into a single, walk-away platform. Featuring 8 pipetting channels and advanced liquid handling capabilities, the system delivers high-purity, contaminant-free nucleic acids in high concentrations, ensuring robust support for downstream applications including NGS, PCR, MLPA, and long-read sequencing.
Technical Specifications
- Dimensions: 0.865 m (W) × 2.285 m (D) × 1.94 m (H)
- Sample Throughput: 1–192 samples per run
- Sample Volume: 50 µL – 10 mL
- Applications: cfDNA, DNA, RNA, Viral Nucleic Acids
- User Interface: Touchscreen with intuitive software
- Traceability: Integrated barcode scanner, LIMS-compatible
Key Benefits
End-to-End Workflow Automation
Handles all steps from sample transfer to PCR setup, reducing manual intervention and minimising human error.
Validated, Single-Supplier Solution
Combines extraction kits and instrumentation from Revvity for a streamlined, consistent workflow with high reproducibility.
Compact High-Throughput Capability
Processes up to 192 samples per run with sample volumes up to 10 mL, making it ideal for blood donor screening, pathogen surveillance, and genetic studies.
Patented M-PVA Magnetic Bead Technology
Delivers high yields, integrity, and purity of nucleic acids across diverse sample types.
Applications
- cfDNA and Viral Nucleic Acid Extraction
- DNA/RNA Isolation from blood, saliva, plasma, swabs, and wastewater
- High-resolution SNP genotyping
- Pathogen surveillance (e.g., SARS-CoV-2, HIV, HBV, HCV, malaria)
- Biobanking and population studies
Key Features
Performance
- Delivers ultra-pure nucleic acids suitable for NGS, PCR, MLPA, and long-read sequencing.
- Ensures high sensitivity and traceability in high-throughput screening, as demonstrated in blood donor screening (up to 552 blood bags/day).
Flexibility
- Processes 1–192 samples/run across a range of sample volumes (50 µL – 10 mL).
- Supports diverse tube formats and sample types in a single run.
- Enables on-deck normalisation, assay setup, and eluate transfer.
Automated Traceability
- Integrated 1D/2D barcode scanning.
- LIMS-compatible log files and customizable run reports.
- Full reagent and tip tracking for 100% traceability.
Efficiency
- Cost-effective buffer dispensing without expensive cartridges.
- Supports multiple kits with a switch box for seamless workflow transitions.
- On-deck heating, cooling, and shaking options for optimised protocols.
User-Friendly Operation
- Fast startup with intuitive software and guided setup.
- LED status lights and email notifications for error reporting.
- UV disinfection and drop cover for enhanced safety and contamination prevention.
Configurations and Processing Options
The chemagic™ Prime™ Instrument can be configured with two chemagic Rod Heads for flexibility in throughput and sample volume:
| Rod Head | Sample Capacity | Sample Capacity | Sample Capacity |
|---|---|---|---|
| chemagic 24 Rod Head | 1–48 | 200 µL – 10 mL | ~75 min for 4 mL blood |
| chemagic 96 Rod Head | 1–192 | 50 µL – 1.5 mL | ~55 min for 400 µL blood |
Exemplary Workflows
- High-Throughput Blood Donor Screening: Traceable detection of HIV, HBV, HCV, and malaria with high sensitivity.1
- Autism Genetic Studies: High-quality DNA extraction from saliva for high-resolution SNP genotyping.2
- Pathogen Surveillance: Sensitive detection of SARS-CoV-2 in blood, swabs, and wastewater for public health monitoring.3-6
chemagic™ Prime Kits
Dedicated kits for DNA and RNA extraction from blood, saliva, plasma, and other sample matrices are available, featuring:
- Ready-to-use reagents
- Included plastic consumables
- Patented chemagic™ M-PVA Magnetic Bead Technology for reliable results
Supporting Literature
- Costa E, Rocha D, Lopes JIF, et al. Detection of Plasmodium spp. in asymptomatic blood donors by the new Brazilian NAT PLUS HIV/HBV/HCV/Malaria Bio-Manguinhos kit. Transfusion. 2024;64(3):501-509. doi:10.1111/trf.17726
- Bui DT, Ton ANV, Nguyen CTD, et al. Pathogenic/likely pathogenic mutations identified in Vietnamese children diagnosed with autism spectrum disorder using high-resolution SNP genotyping platform. Sci Rep. 2024;14(1):2360. Published 2024 Jan 29. doi:10.1038/s41598-024-52777-y
- Döhla M, Schulte B, Wilbring G, et al. SARS-CoV-2 in Environmental Samples of Quarantined Households. Viruses. 2022;14(5):1075. Published 2022 May 17. doi:10.3390/v14051075
- Lou EG, Sapoval N, McCall C, et al. Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater. Sci Total Environ. 2022;833:155059. doi:10.1016/j.scitotenv.2022.155059
- Streeck H, Schulte B, Kümmerer BM, et al. Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany. Nat Commun. 2020;11(1):5829. Published 2020 Nov 17. doi:10.1038/s41467-020-19509-y
- LaTurner ZW, Zong DM, Kalvapalle P, et al. Evaluating recovery, cost, and throughput of different concentration methods for SARS-CoV-2 wastewater-based epidemiology. Water Res. 2021;197:117043. doi:10.1016/j.watres.2021.117043
Frequently Asked Questions (FAQs): chemagic™ Prime™ Instrument
Q: What is the chemagic™ Prime™ Instrument used for?
A: It is a fully automated system for DNA and RNA extraction, optional normalisation, and PCR setup in a single walk-away platform for high-throughput research workflows.
Q: How many samples can the chemagic™ Prime™ process per run?
A: It can process 1 to 192 samples per run, making it suitable for high-throughput labs.
Q: What sample volumes can it handle?
A: It can process sample volumes from 50 µL to 10 mL, offering flexibility across different sample types.
Q: What types of samples can the chemagic™ Prime™ process?
A: It can process blood, saliva, plasma, swabs, wastewater, and other biological samples for DNA/RNA extraction.
Q: Is this instrument suitable for diagnostic procedures?
A: No, the chemagic™ Prime™ Instrument is for research use only and is not intended for diagnostic procedures.
Q: What technology does the chemagic™ Prime™ Instrument use?
A: It uses Revvity’s patented M-PVA Magnetic Bead Technology, providing high yields, purity, and integrity of nucleic acids.
Q: What are the dimensions of the chemagic™ Prime™ Instrument?
A: It measures 0.865 m (W) × 2.285 m (D) × 1.94 m (H).
Q: What applications are supported by the chemagic™ Prime™?
A: Applications include cfDNA and viral nucleic acid extraction, DNA/RNA isolation from various sample types, NGS, PCR, MLPA, long-read sequencing, high-resolution SNP genotyping, pathogen surveillance, biobanking, and population studies.
Q: How does the instrument support workflow efficiency?
A: It automates the full workflow from sample transfer to PCR setup, reducing manual interventions, supporting on-deck heating, cooling, shaking, UV disinfection, and using intuitive touchscreen software for easy setup.
Q: Does the chemagic™ Prime™ support LIMS integration and traceability?
A: Yes, it includes integrated 1D/2D barcode scanning, LIMS-compatible log files, customizable reports, and full reagent and tip tracking for complete traceability.
Q: How does the chemagic™ Prime™ contribute to high-throughput research?
A: It enables fast, reliable nucleic acid extraction and PCR setup for high-volume labs, supporting pathogen surveillance, genetic studies, and blood donor screening with high sensitivity and reproducibility.
Q: What user-friendly features are included with the instrument?
A: It offers an intuitive touchscreen interface, LED status lights, email notifications for errors, and a guided setup for fast startup and operation.
Q: What kits are available for use with the chemagic™ Prime™ Instrument?
A: Dedicated chemagic™ Prime kits are available for DNA and RNA extraction from blood, saliva, plasma, and other sample types, featuring ready-to-use reagents and included consumables.
Q: What are the processing configurations available for the chemagic™ Prime™ Instrument?
A: It offers interchangeable rod heads:
- chemagic 24 Rod Head: 1–48 samples, 200 µL – 10 mL, ~75 min for 4 mL blood.
- chemagic 96 Rod Head: 1–192 samples, 50 µL – 1.5 mL, ~55 min for 400 µL blood.
| Brand | Revvity |
|---|
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