High-Throughput Microfluidic Electrophoresis for Protein and Nucleic Acid Analysis
Overview
The LabChip® GXII Touch™ HT Protein Characterization System is an advanced microfluidic platform designed for the rapid and reproducible analysis of protein and nucleic acid samples. By automating traditional electrophoresis methods, this system streamlines workflows, reduces sample preparation time, and enhances throughput, making it suitable for various stages of biotherapeutic development and genomic research.
Key Features
Microfluidic Electrophoresis Technology: Enables rapid separation and analysis with minimal sample input.
High Throughput Capability: Processes up to 384 samples per run, with analysis times as short as 42 seconds per sample.
Versatile Assay Support: Compatible with a range of assays, including protein quantitation, molecular weight sizing, purity assessment, glycan profiling, and charge variant analysis.
User-Friendly Interface: Touchscreen operation simplifies workflow setup and execution.
Regulatory Compliance: Supports 21 CFR Part 11 compliance with features like audit trails and electronic signatures.
Data Integration: Facilitates seamless data export to LIMS or network directories.
Applications
Protein Analysis: Quantitation, molecular weight determination, purity assessment, glycan profiling, and charge variant analysis.
Nucleic Acid Analysis: DNA and RNA quantitation, sizing, and quality assessment.
Biotherapeutic Development: Supports Quality by Design (QbD) and Design of Experiments (DoE) approaches in process development.
Why Choose the LabChip® GXII Touch™ HT Protein Characterization System?
Efficiency: Automates complex workflows, reducing hands-on time and increasing sample throughput.
Accuracy: Provides high-resolution data comparable to traditional capillary electrophoresis methods.
Flexibility: Accommodates a wide range of assays and sample types, making it adaptable to various research needs.
Compliance: Built-in features support regulatory requirements for data integrity and traceability.
Frequently Asked Questions (FAQs): LabChip® GXII Touch™ HT Protein Characterization System
Q: What types of assays are compatible with the LabChip® GXII Touch™ HT Protein Characterization System?
A: The system supports multiple assays, including protein quantitation, molecular weight sizing, purity assessment, glycan profiling, and charge variant analysis.
Q: Is the LabChip® GXII Touch™ HT Protein Characterization System suitable for high-throughput applications?
A: Yes, it can process up to 384 samples per run, with rapid analysis times, making it ideal for high-throughput environments.
Q: How does the system ensure data integrity and compliance?
A: It includes features such as audit trails, electronic signatures, and secure data export options to support 21 CFR Part 11 compliance.
Q: Can the system be integrated with existing laboratory information management systems (LIMS)?
A: Yes, it facilitates seamless data export to LIMS or network directories, enhancing data management and workflow integration.