Name: PromethION
Brand: Oxford Nanopore Technologies
SKU: PromethION
Availability: OutOfStock

The PromethION devices deliver high-coverage nanopore sequencing in formats ranging from modular, fully integrated devices to high-throughput solutions. Each flow cell can deliver the lowest price per Gb for nanopore sequencing.

Why PromethION? Key Features:

Flexible, on-demand sequencing and up to 13.3 Tb data*: Run up to 48 independently addressable, high-capacity PromethION Flow Cells. (* Theoretical max output when the system is run for 72 hours at 400 bases/second. Outputs may vary according to library type, run conditions, etc.)
Ultra-high throughput: Generate terabases of data—sstreamed in real-time for immediate analysis.
Powerful, high-performance compute: Alleviate data analysis bottlenecks. Analyse data in real-time with 4 NVIDIA A-Series GPUs.

Learn more about the technology here: https://nanoporetech.com/platform/technology/

Which PromethION device is right for me?

Not sure which PromethION device you need? See below for the number of flow cells you can run on a PromethION 2 device, a PromethION 24 or a PromethION 48 each year.

Flow cell specifications:

100-200 Gb native gDNA reads (read N50 ~25 kb)
Multiplexed sequencing of up to 96 samples with PCR or PCR-free barcoding
>100 million cDNA reads for isoform-level analysis
50-100 Gb ultra-long native DNA reads (>50 kb read N50)
>200 Gb on metagenomic samples (read N50 ~ 10 kb)

Plus: direct methylation detection, chromatin confirmation capture with Pore-C, direct RNA sequencing, read lengths from short (20 bases) to ultra-long (>4 million bases)

PromethION 2

Choose PromethION 2 devices for flexible, high-yield sequencing, in a compact, accessible design. Utilising flow cells that generate hundreds of gigabases, enables PromethION-scale benefits in small to medium-sized labs — including cores and commercial service providers. Suitable for users with lower sample processing requirements, up to ~200 flow cells per year. The PromethION 2 devices allow users to explore their applications and projects, before scaling up to a PromethION 24 or PromethION 48 device if required.

PromethION 2 Integrated

A self-contained benchtop nanopore sequencer containing a powerful GPU and running two high-output PromethION Flow Cells.

Key Features:

Two high-output flow cells can be operated individually or together for flexible, on-demand sequencing.
High-performance: 16 TB SSD and 64 GB RAM
High-resolution touchscreen display or existing computer infrastructure
Flexible, on-demand sequencing with powerful NVIDIA A-Series GPU for onboard data analysis

PromethION 2 Solo

A compact sequencer for two PromethION Flow Cells, utilising resource within the GridION or other suitable compute, including laptops, to quickly enable accurate, high output nanopore sequencing.

Key Features:

Two high-output flow cells delivering up to 580 Gb of data.
Connect to GridION or existing computer infrastructure.
Flexible, on-demand sequencing run flow cells individually or together.

PromethION 24/48

Two PromethION models are available for high-throughput sequencing projects: the PromethION 24 (P24) and PromethION 48 (P48), respectively operating up to 24 and 48 flow cells at once. Both systems are deployed with the powerful PromethION A-Series tower, utilising 4 NVIDIA A-Series GPUs for real-time data handling.

Key Features:

Read length: Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)
Dimensions (Compact benchtop device with compute module): PromethION Sequencer: Size: W 590 mm, H 190 mm, D 430 mm; Weight: 28 kg; PromethION A-Series Data Acquisition Unit: Size: W 178 mm, H 440 mm, D 470 mm; Weight: 25 kg
Up to 277 Gb per flow cell* (Total device output as much as): Up to 6.6 Tb PromethION 24*; Up to 13.3 Tb PromethION 48* (* Theoretical max output when the system is run for 72 hours at 400 bases/second. Outputs may vary according to library type, run conditions, etc.)
On-demand (Sequence what you need, when you need it): Run flow cells individually or together — no more sample batching; Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell; Run multiple DNA or RNA experiments at once; Barcode for even more samples; Suitable for high-throughput and service labs
Accessible: No capital cost; Small footprint — suitable for any lab; Easy installation with comprehensive support
High-performance compute (Sequencing and analysis in one powerful device): Latest generation CPU; 4 NVIDIA A-Series GPUs; 60 TB SSD data storage; 512 GB RAM; Preloaded with Ubuntu OS and MinKNOW

PromethION 24

Offering the flexibility of 24 independently controllable, high-output flow cells and leveraging state-of-the-art algorithms and GPU technology, PromethION 24 (P24) provides single or multiple users with on-demand access to terabases of sequencing data.

PromethION 48

PromethION 48 (P48), Oxford Nanopore Technologies' most powerful sequencing device, delivers twice the capacity and output of P24 — ideal for large- and production-scale sequencing projects.