GridION

GridION Mk1 is a cost-effective and compact benchtop system offering on-demand sequencing with integrated real-time data processing. With the capacity to run five flow cells either concurrently or individually and a total yield of up to 150 Gb, GridION Mk1 provides busy labs and service providers with cost-efficient access to the advantages of long-read, real-time nanopore sequencing. You may choose to use as much or as little of this total resource at any one time. GridION Mk1 also allows you to offer nanopore sequencing as a service. Integrated, high-performance data processing alleviates the need for complex IT infrastructure.

The GridION Mk1 has five sequencing ports where MinION/GridION Flow Cells or Flongle Adapters with flow cells can be connected, as well as a high-performance integrated computer and basecalling accelerator. The device can basecall, in real-time, the data generated by five flow cells or flongles. The current chemistry and software enable the generation of up to 150 Gbases of data during a GridION Mk1 run. Setting up a GridION Mk1 requires minimal infrastructure with no need for facility upgrades. A new device requires only a power source and network connectivity via an Ethernet port. There are three USB 3.0 ports available for peripherals, e.g. keyboard and mouse. Monitors must be connected via DisplayPort. The device is powered from the mains via the C13 cable and is switched on via a power button on the front.

Why GridION? Key Features:

• Read length: Nanopores read the length of DNA or RNA presented to them—from short to ultra-long (longest >4 Mb).
• Dimensions: Compact benchtop device with integrated compute suitable for any lab. Size: W 370 mm, H 220 mm, D 365 mm; Weight: 11 kg.
• 240 Gb output*: Up to 48 Gb per MinION Flow Cell / 2.8 Gb per Flongle Flow Cell*. (*Theoretical max output when the system is run for 72 hours (or 16 hours for Flongle) at 400 bases/second. Outputs may vary according to library type, run conditions, etc.)
• On-demand: Sequence what you need, when you need it. Run flow cells individually or together — no more sample batching; Mix MinION and Flongle Flow Cells to suit experimental needs; Run multiple DNA or RNA experiments at once; Barcode for even more samples.
• Accessible: No capital cost; simple plug-and-play operation; integrated compute—minimal IT infrastructure required.
• Powerful, integrated compute: Sequencing and analysis in one powerful device. Latest generation CPU / GV100 GPU accelerator; 64 GB RAM / 4 TB SSD storage; Ethernet connectivity; Instrument control and data analysis software

Learn more about the technology here: https://nanoporetech.com/platform/technology/

The GridION is suitable for a wide range of applications, including:

• Larger genomes or projects
• Whole transcriptomes (direct RNA or cDNA)
• Large numbers of samples