Cellaca MX High-Throughput Cell Counter
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- Configurations: BF (brightfield only), FL2 (brightfield + 2 fluorescent channels), FL5 (brightfield + 5 fluorescent channels) — all field-upgradeable
- Batch size: Up to 24 samples per run
- Run time: 48 seconds (brightfield) / under 3 minutes (fluorescence)
- Minimum sample volume: 25 µl per well
- Cell size range: 5–80 µm
- Concentration range: 1×10⁵ – 1×10⁷ cells/ml
- Dimensions (W x D x H): 33 cm x 41 cm x 33 cm
- Weight: 18 kg (BF) / 19 kg (FL2, FL5)
- Operating system: Windows 11
- Automation compatible: Yes (optional API)
- 21 CFR Part 11: Optional module available
For research use only. Not for use in diagnostic procedures.
Need a customised solution?
Optional accessories are available for purchase separately. If your order needs a customised configuration, our technical specialists will follow up with full details before your order is finalised. Contact us via the enquiry form or sales@lasec.com.
Installation, training and special delivery
Some products require installation, training, or special delivery (such as tail-lift trucks, extra labour, or hazardous material packaging). If your order needs this, we'll contact you with the additional cost before dispatch, so your final invoice may differ from the listed price.
Ordering from outside South Africa
Online ordering is currently limited to South African customers, but our full range is still available. Log an enquiry or email international@lasec.com and our international sales team will assist you through our traditional sales channels.
DISCLAIMER: All product images are for illustrative purposes only. Actual products may vary slightly in colours, controls, and visible features.
Availability:On Request
SKU
IREVMX-AOPI
BrandRevvity
Product Overview
The Cellaca MX is a microplate-based automated cell counter that processes up to 24 samples in a single batch, with fluorescence runs completed in under 3 minutes. Three configurations span brightfield-only through to five-channel fluorescence, and each is field-upgradeable, so the instrument grows with your experimental needs. Built-in mixing technology, simultaneous imaging and analysis, declustering algorithms for clumpy samples, and over 200 preloaded cell types make it suited to routine viability work and more demanding cell-based assays alike.
Key Performance Figures
- Batch size: 24 samples
- Brightfield run time: 48 seconds
- Fluorescence run time: <3 minutes
- Sample volume: 25 µl minimum
- Cell size range: 5–80 µm
- Concentration range: 1×10⁵ – 1×10⁷
Configurations
All three configurations are field-upgradeable. Select based on your current assay requirements.
| Cellaca MX BF Brightfield only | Cellaca MX FL2 Brightfield + 2 fluorescent | Cellaca MX FL5 Brightfield + 5 fluorescent | |
|---|---|---|---|
| Channels | Brightfield (1 channel) | Brightfield, Green, Red (4 channels) | BF, Blue, Green, Red, Far Red (14 ch) |
| Excitation LED | N/A | 470, 527 nm | 365, 470, 527, 620 nm |
| Emission filters | N/A | 534, 655 nm | 452, 534, 605, 655, 692 nm |
| Compatible dyes | Trypan Blue | Trypan Blue, AO/PI, GFP | Trypan Blue, AO/PI, Hoechst, DAPI, GFP, RFP, CMFDA, Calcein AM, 7AAD, Annexin V |
| Run time (24 samples) | 48 seconds | 48 sec (BF) / <3 min (FL) | 48 sec (BF) / <3 min (FL) |
| Weight | 18 kg (40 lbs) | 19 kg (42 lbs) | 19 kg (42 lbs) |
All configurations: sample volume 25–100 µl per well; total well volume 50–200 µl; cell size range 5–80 µm; concentration range 1×10⁵–1×10⁷. Dimensions: 33 cm (W) x 41 cm (D) x 33 cm (H) [13 in x 16 in x 13 in]. Operating system: Windows 11.
Workflow Capabilities
- Process up to 24 samples simultaneously in a microplate format — no reloading of individual slides between batches
- Simultaneous imaging and analysis: results from the first well are available for review before the full plate acquisition completes
- Revvity's patented in-plate mixing technology (U.S. Pat. No. 11,911,764; patents pending: EP3755789A1 and CN201980026197.7) allows cell sample and viability dye to be mixed within a single well using a built-in capillary mechanism, eliminating the need for separate tube preparation steps
- Autofocus before each acquisition ensures consistent image quality across the plate
- Out-of-range alerts notify the operator when the cell count is too low or too high, and suggest corrective action, including concentration or dilution factors
- The declustering algorithm identifies and counts individual cells within clumped samples to maintain count accuracy
- Over 200 preloaded cell types with optimised settings; build custom assays or select from those already included in the software
- Time course reporting with growth curve generation across multiple samples and time points
- Automatic calculation of parameters, including doubling time for individually labelled samples
- Robotic integration via an optional API for full automation compatibility
- Configurable reports exportable as CSV, Excel, Word, or PDF; statistical analysis, images, graphs, charts, and tables can be included
- Multi-language support. Over 7,000 languages are available for both the interface and reporting
Cell-Based Assay Capabilities
Available with FL2 and FL5 configurations. The Cell Fitness Panel covers the following parameters:
- Viability
- Vitality
- Apoptosis
- Reactive oxygen species (ROS)
- Mitochondrial membrane potential
- Protein expression (GFP, RFP)
Fluorescent nuclear stains (acridine orange/propidium iodide) reduce red blood cell, platelet, and debris interference in samples such as PBMCs, patient samples, tumour digests, and debris-rich preparations.
Optional Modules
21 CFR Part 11 compliance module
- User login with passwords and user-assigned permissions
- Audit trail and error log files
- Electronic signatures
IQ-OQ qualification
Installation qualification (IQ) and operational qualification (OQ) option available for all three configurations
| Dimensions (W x D x H) | 33 cm x 41 cm x 33 cm (13 in x 16 in x 13 in) |
| Weight — BF configuration | 18 kg (40 lbs) |
| Weight — FL2 and FL5 configurations | 19 kg (42 lbs) |
| Operating system | Windows 11 |
| Technology | Matrix software |
| Imaging modality | Fluorescence, brightfield |
| Automation compatible | Yes (optional API) |
| 21 CFR Part 11 ready | Yes (optional module, all configurations) |
| IQ-OQ option | Yes (all configurations) |
| Field upgradeable | Yes — BF upgradeable to FL2; FL2 upgradeable with additional colours |
| Unit size | 1 each |
For research use only. Not for use in diagnostic procedures. Patent: U.S. Pat. No. 11,911,764. Patents pending: EP3755789A1 and CN201980026197.7.
Frequently Asked Questions (FAQs): Cellaca MX High-Throughput Cell Counter
Q: How much volume of my sample do I need to perform a count?
A: The minimum loading volume of the stained sample in the counting plate is 50 µl. Typically, you will stain your cell sample 1:1 with AOPI dual-fluorescent viability dye, so you can perform a cell count with as little as 25 µl of cell sample.
Q: Can I save the plate for later if I only have a few samples to count?
A: Yes, load the counting plate with as many or as few samples as you want to count. The Cellaca software will allow you to indicate which wells contain samples you wish to count, and the rest of the plate can be saved for later use.
Q: Are the counting plates compatible with multi-channel pipettes?
A: Yes, the counting plates are compatible with multi-channel pipettes, making it fast and easy to stain and prep your samples. The Cellaca is also compatible with liquid handlers and automation platforms and has an optional automation license add-on, making it easy to scale up your throughput.
Q: What daily start-up or shut-down cycles do I need to run?
A: There are no daily start-up or shut-down cycles for the Cellaca because there are no internal fluidics and nothing that needs to be cleaned or could clog. The Cellaca uses LEDs as a light source. The only prep you need to do is turn on the instrument and start up the software, and the Cellaca is ready to count your samples right away.
Q: How does the Cellaca count challenging or messy cell types?
A: The Cellaca is designed to identify live and dead nucleated cells, even in very messy samples with RBCs and debris or in irregular-shaped cell populations. By using the AOPI dual-fluorescence viability dye, only nucleated cells are counted, and RBCs and debris are ignored (this method is so specific, it even works in whole blood without lysing!). The Cellaca will show you the images it captured and which cells were counted so that you can visually verify the results and trust your data.
| Brand | Revvity |
|---|
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