Capitainer®B50 Volumetric Dried Blood Spot Card
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- Sample type: Whole blood (finger stick)
- Sample volume: 2 × 50 ± 0.98 µl per card, volumetric
- Sample disc diameter: 6 mm
- Precision: CV < 2%; SD < 0.98 µl
- Outlier rate (over/under-fill): < 1% (> 3 SD; success run, n = 300)
- Risk of no sample: < 1%
- HCT range: 25–55%
- Operating temperature: +15°C to +35°C
- Operating relative humidity: 15–90%
- Use window: Within 30 minutes of opening package
- Drying: Integrated paper-based drying pouch; no user drying step required
- Card material: Ahlstrom grade 320
- Product dimensions: 78 × 43 × 4 mm
- Sample storage: Ambient temperature; freezer storage extends stability
- Regulatory status: CE-IVD (IVDR), EU 2017/746; FDA Class 1; Research Use Only elsewhere
- Pack size: 50 pcs box
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Optional accessories are available for purchase separately. If your order needs a customised configuration, our technical specialists will follow up with full details before your order is finalised. Contact us via the enquiry form or sales@lasec.com.
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DISCLAIMER: All product images are for illustrative purposes only. Actual products may vary slightly in colours, controls, and visible features.
Availability:On Request
SKU
DCAP210-0025
BrandCapitainer
Product Overview
High-volume volumetric microsampling for quantitative DBS analysis
The Capitainer®B50 is a volumetric dried blood spot card designed for applications requiring a larger sample volume. Collecting 2 × 50 µl of whole blood from a finger stick, it extends the range of analytes and analytical techniques accessible through microsampling. An integrated paper-based drying pouch allows the sample to dry during transport, with no user drying step required.
The card's microfluidic metering technology provides an exact, volumetrically defined sample, overcoming the haematocrit-dependent variability of conventional DBS cards and enabling quantitative analysis.
- Sample volume: 2 × 50 µl whole blood, volumetric
- Precision: CV < 2% SD < 0.98 µl
Key Features
- Accurate: Automatically meters 2 × 50 µl of blood
- Reliable: Designed to minimise risk of over- or under-fill
- Trusted: Integrated successful-sampling indicator
- Protected sample: Sample enclosed and protected from contamination
- User-friendly: Multiple drops applied until metering channel is filled
Volumetric DBS vs conventional dried blood spot cards
The limitation of conventional DBS
Dried blood spot sampling has been used since the 1960s, initially for newborn screening. Conventional DBS cards, however, lack volumetric control: because blood viscosity varies with haematocrit (HCT), the same volume of blood produces a differently sized spot at different HCT values. A standardised sub-punch from a conventional DBS card therefore does not yield a precisely defined volume, which restricts conventional DBS to qualitative or semiquantitative analysis.
How Capitainer®B50 addresses this
The Capitainer®B50 uses microfluidic technology to meter blood into a pre-cut disc. Because the entire, volume-defined disc is used for analysis, the haematocrit effect is removed, and the sample can support quantitative tests. Methods have been published for over 2 000 analytes using conventional DBS; Capitainer's volumetric approach provides a route to developing those into quantitative assays.
Application Areas
The Capitainer®B50's larger sample volume makes it suited to applications where the 10 µl output of the Capitainer®B10 cards is insufficient.
- Quantitative dried blood spot testing across a broad analyte range
- Remote and at-home finger-stick blood collection without laboratory or phlebotomy infrastructure
- Research studies requiring postal return of volumetrically precise blood samples
- Applications requiring ambient-temperature transit of dried blood samples
Sampling and Drying
The user applies multiple drops of blood to the device until the metering channel is filled. No single large drop is required. The integrated paper-based drying pouch allows the collected sample to dry during transport; no separate drying step is required by the user.
The card must be used within 30 minutes of opening the package.
Blood-stained materials and sharps: handle and dispose of according to local regulations for biological waste and sharps.
Regulatory Status
- EU classification: CE-IVD (IVDR), registered under Regulation (EU) 2017/746
- US classification: FDA-approved, Device Class 1
- Other regions: Where neither registration applies, supplied as Research Use Only (RUO) for research and non-diagnostic activities
- Assay validation responsibility: End-users and laboratories are responsible for validating assay results from Capitainer products
| Technical Data | |
|---|---|
| Sample type | Whole blood (finger stick) |
| Sample volume | 2 × 50 ± 0.98 µl |
| Sample disc diameter | 6 mm |
| Product dimensions | 78 × 43 × 4 mm |
| Card material | Paper, Ahlstrom grade 320 |
| Sampling indicator | Integrated successful-sampling indicator |
| Drying | Integrated paper-based drying pouch; no user drying step required |
| Performance | |
| Reproducibility | SD < 0.98 µl; CV < 2% |
| Outlier rate (over- or under-fill) | < 1% (deviation > 3 SD) * |
| Risk of no sample | < 1% * |
| Operating Conditions (During Use) | |
| Operating temperature | +15°C to +35°C |
| Relative humidity | 15% to 90% |
| Haematocrit range | 25% to 55% |
| Use window after opening | Must be used within 30 minutes of opening the package |
| Collected Sample Storage | |
| Ambient storage | Collected samples may be stored at room temperature |
| Extended stability | Sample discs may be stored in the freezer to extend analyte stability |
| Analyte-specific stability | Must be validated by the responsible laboratory; refer to DBS literature for guidance on individual analytes |
| Compliance | |
| EU classification | CE-IVD (IVDR), Regulation (EU) 2017/746 |
| US classification | FDA-approved, Device Class 1 |
| Other regions | Research Use Only (RUO) where equivalent registration does not apply |
| Manufacturer | |
| Manufacturer | Capitainer AB |
| Address | Solna Torg 19, SE-171 45 Solna, Sweden |
* Success run testing with safety delay: ΔT > 6 seconds, 35% and 45% haematocrit, reliability 99%, confidence 95%, n = 300, 0 failures accepted.
Frequently Asked Questions about the Capitainer®B50
Q: What makes the Capitainer®B50 different from a conventional dried blood spot card?
A: Conventional DBS cards produce spots of variable size depending on the haematocrit of the sample, which limits them to qualitative or semiquantitative analysis. The Capitainer®B50 meters blood into a pre-cut disc using microfluidic technology, delivering a precisely defined volume regardless of haematocrit variation. This enables quantitative analysis from a dried blood spot.
Q: How is blood applied to the Capitainer®B50?
A: Multiple drops of finger-stick blood are applied to the card until the metering channel is filled. No single large drop is required, and the sampling indicator confirms when a successful sample has been collected.
Q: Does the sample need to be dried before posting?
A: No. The Capitainer®B50 includes an integrated paper-based drying pouch that allows the collected sample to dry during transit. No separate drying step is required from the user.
Q: What is the difference between the Capitainer®B50 and the Capitainer®B10Vanadate?
A: The Capitainer®B50 collects 2 × 50 µl and is designed for general-purpose quantitative DBS across a wide analyte range. The Capitainer®B10Vanadate collects 2 × 10 µl and is specifically developed for PEth (alcohol biomarker) testing, incorporating sodium metavanadate to prevent post-sampling PEth formation.
Q: How should collected samples be stored?
A: Collected samples may be stored at room temperature. For extended stability, the sample disc may be stored frozen. Stability of specific analytes should be validated by the responsible laboratory.
| Brand | Capitainer |
|---|
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